Product Center
With electronic materials as the core, while also focusing on the development of highly challenging pharmaceutical intermediates.
- Product Description
- Physical properties
- Product Advantages
- Application
-
- Commodity name: MPPE-1
- 产品副标题: CAS:5855-13-4
Structure
Name
4-MBA; p-Maleimidobenzoic acid
CAS
17057-04-4
Molecular Fomular
C11H7NO4
Molecular Weight
217.18
-
Main Category
Subcategory
Description
bio-labeling
Protein and antibody labeling
The fluorescent dyes, biotin, enzymes or other reporting molecules are linked to the protein or antibody with free sulfhydryl groups through their carboxyl groups. First, the carboxyl groups of 4-MBA are activated using EDC/NHS, allowing them to react with the amino groups of the reporting molecules; then, the generated maleimide-derivatized reporting molecules can specifically bind to the sulfhydryl groups on the protein.
Peptide (protein) cross-linking, complexing spatial expression
Fluorescent dyes, biotin, enzymes or other reporting molecules are linked to a molecule with a carboxyl group through their carboxyl groups. This molecule is used to connect a molecule containing an amino group (such as a polypeptide or protein) with another molecule containing a thiol group, for the study of molecular interactions or the construction of complex biological complexes.
Preparation of biosensors
When constructing a biosensor, the materials are used to orientally fix the biological recognition elements (such as antibodies, enzymes) onto the surface of the sensor chip, maintaining their biological activity.
medicine
Antibody-drug conjugates (ADCs)
In the construction of ADCs, it can be used to attach cytotoxic drugs to monoclonal antibodies. Antibodies usually generate sulfhydryl groups by reducing their inter-chain disulfide bonds, and then efficiently and specifically bind to the malonylhydrazine groups.
---
---
Material modification or functionalization
Antibody-drug conjugates (ADCs) modified with maleimide resin (either through physical blending or chemical introduction)
Such as chemical modification of polyphenylene ether and amino resins using bismaleimide;
Such as copolymerization modification with acryl groups (acryl phenol oxides, acryl bisphenol A) and benzoxazine compounds.
Product Introduction
|
Structure |
|
|
Name |
4-MBA; p-Maleimidobenzoic acid |
|
CAS |
17057-04-4 |
|
Molecular Fomular |
C11H7NO4 |
|
Molecular Weight |
217.18 |
Product Inquiry
Please complete the relevant information, and our customer service team will contact you promptly to send you the materials.
Contact Information
Switchboard:025-84823631
Sales:025-84823350
General Manager:13601462659
Email:admin@yspharma.com
Address: Rooms 404–408 and 309–313, Building F7, Jiangsu Life Science Innovation Park, No. 9 Weidi Road, Xianlin Subdistrict, Qixia District, Nanjing, Jiangsu Province
Copyright © 2026 Yuanshu Pharmaceutical Technology Co., Ltd.
-
-
Sales
-
General Manager
-
Email box
-
